Cisplatin immunotherapy
WebDec 5, 2024 · Rossi A, Di Maio M, Chiodini P, et al. Carboplatin- or cisplatin-based chemotherapy in first-line treatment of small-cell lung cancer: the COCIS meta-analysis of individual patient data. J Clin Oncol 2012; 30:1692. Horn L, Mansfield AS, Szczęsna A, et al. First-Line Atezolizumab plus Chemotherapy in Extensive-Stage Small-Cell Lung Cancer. WebApr 12, 2024 · The combination of the chemotherapy drugs cisplatin and paclitaxel has long been the standard treatment for women with advanced or recurrent endometrial cancer. But treatment options for these two groups of patients have changed recently, largely because of advances in immunotherapy.
Cisplatin immunotherapy
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WebNov 23, 2024 · Recently, immunotherapy has demonstrated clinical activity in extensive-stage SCLC (ES-SCLC). The CASPIAN trial assessed durvalumab, with or without tremelimumab, in combination with etoposide plus either cisplatin or carboplatin (platinum-etoposide) in treatment-naive patients with ES-SCLC. Methods: WebTaken together, these results demonstrate that statins, administered in combination with anti-PD-1 antibody, could enhance the anticancer effect of cisplatin and potentiate the efficacy of immunotherapy for HNSCC and present a rationale for repurposing statins as an adjuvant immunotherapeutic option for HNSCC.
WebCisplatin is believed to augment the effects of radiation by inhibiting the repair of radiation-induced sublethal damage and by sensitizing hypoxic cells to radiation. 9,30 Because of its... WebAug 19, 2024 · Guru P. Sonpavde, MD: In cisplatin-ineligible patients, you can make a case to test it just to give the patient the option. Essentially, in PD-L1–low patients, I don’t consider first-line immune checkpoint inhibitors. It might make a difference in some patients who really strongly want immunotherapy. Petros Grivas, MD, PhD: Thank you.
Web(sis-PLA-tin) Cisplatin is a chemotherapy drug that contains the metal platinum. It stops or slows growth of cancer cells and other cells that grow rapidly by damaging their DNA. … WebApr 12, 2024 · The combination of the chemotherapy drugs cisplatin and paclitaxel has long been the standard treatment for women with advanced or recurrent endometrial cancer. But treatment options for these two groups of patients have changed recently, largely …
WebSurgery, chemotherapy, radiotherapy and immunotherapy are currently the main options for cancer treatment. However, ... CAFs-derived IL-6 could upregulate CXCR7 in esophageal squamous cell carcinoma and promote resistance to cisplatin via the JAK/STAT3 pathway (Qiao et al., 2024).
WebCisplatin side effects may be quite manageable. There are many options to help minimize or prevent the side effects of cisplatin. There is no relationship between the presence or … in wall echo dot mountWebIMFINZI may be used with the chemotherapy medicines etoposide and carboplatin or cisplatin as your first treatment when your SCLC has spread within your lungs or to other parts of the body (extensive-stage small cell lung cancer, or ES-SCLC). in wall dryer vent lint trapWebMar 27, 2024 · (1) Background: Malignant pleural mesothelioma (MPM) is a rare but aggressive tumor arising from the pleural surface. For relapsed MPM, there is no accepted standard of- are for subsequent treatment. Thus, we aimed to compare the efficacy of chemotherapy, targeting drugs, and immune-checkpoint inhibitors (ICIs) as subsequent … in wall electrical boxesWebOct 9, 2024 · Consent forms for SACT (Systemic Anti-Cancer Therapy) Cancer Research UK Standardised SACT regimen-specific consent forms for Clinicians and healthcare professionals involved with consenting and treating patients with SACT. in wall electrical timersWebTaken together, these results demonstrate that statins, administered in combination with anti-PD-1 antibody, could enhance the anticancer effect of cisplatin and potentiate the … in wall dvd shelvesWebSep 20, 2024 · Cisplatin / pharmacology Dendritic Cells / drug effects Galectin 3 / drug effects Humans Interleukin-10 / metabolism Interleukin-6 / metabolism Lung Neoplasms / drug therapy* Lung Neoplasms / immunology Macrophage-1 Antigen / drug effects Macrophages / drug effects* Mice Polysaccharides / pharmacology* Quality of Life T … in wall electrical panelWebOct 30, 2024 · A key study showing a beneficial immunological effect of cisplatin highlights how cisplatin renders tumour cells more susceptible to the cytotoxic effect of T cells … in wall electric fireplace designs